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Services provided by PharmaResources pharmaceutical chemical R & D team

2020-06-01 15:41:58
Services provided by PharmaResources pharmaceutical chemical R & D team
Detailed introduction:

·Synthesis and confirmation of HTS active compounds

·Mother core design and improvement

·Lead compound optimization

• development of new drug structure-activity relationship based on in vivo and in vitro biological activity data and drug absorption, distribution, metabolism, excretion and toxicity data

• use metabolic analysis to improve the pharmacokinetic characteristics of rodents and achieve pharmacokinetic indicators in vivo

• achieve data indicators of toxicity and safety pharmacology of drugs to rodents through structural modification

• search for clinical candidates with the most ideal physicochemical properties and drug-forming properties through structural modification

• study on the preparation of synthesis process chemistry / amplification

• patent applications

·Clinical candidate drug selection

·Customized cooperation scheme according to customer requirements

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